GHS Update

On 16 July 2025, the United Nations Economic Commission for Europe (UNECE) announced key amendments to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). These changes, approved by the UN Committee of Experts on the Transport of Dangerous Goods and on the GHS at its twelfth session in December 2024, will form the foundation of the eleventh revised edition of the GHS (Rev. 11), scheduled for release in September 2025.

The updates are built upon the tenth revised edition of the GHS, published on 27 July 2023, and introduce essential clarifications and innovations aimed at strengthening hazard communication, aligning with modern science, and addressing emerging environmental concerns.

What should we expect in the 11^th edition?

New Hazard Class: Global Warming Potential (GWP)

One of the most significant changes in GHS Rev. 11 is the introduction of a new hazard class addressing climate impact.

Substances or mixtures containing at least 0.1% of an ingredient listed under the Montreal Protocol with a Global Warming Potential (GWP) must now be classified as “Hazardous by contributing to global warming.”
Labels will require a warning signal word along with a statement such as:
“Harms public health and the environment by contributing to global warming.”

Updates to Health Hazard Classification

Skin Sensitization (Chapter 3.4): Expanded guidance now incorporates non-animal test methods (in vitro, in chemico, and defined approaches), advancing animal-free toxicology.

Refinements of Physical Hazards

Aerosols and Chemicals under Pressure (Chapter 2.3): Refined classification rules ensure consistency across transport and industrial sectors.
Simple Asphyxiants (Annex 11): A new annex provides specific guidance on gases that displace oxygen, enhancing risk recognition in confined spaces.
Desensitized Explosives (Chapter 2.17): New provisions clarify the classification of desensitized explosives, improving safety in handling and transport.

Labeling and SDS Enhancements

Precautionary Statements: Restructured and simplified to improve usability and faster hazard recognition.
Annexes 9 and 10: Updated to harmonize classification strategies for metals and metal compounds, especially regarding long-term aquatic toxicity.
Small Container Labeling: Greater flexibility introduced for containers 100 ml or less, with special provisions for tiny packages (3 ml or less).

The electronic version of GHS Rev. 11 is available free of charge on the UNECE portal. This edition represents a more comprehensive approach to hazard communication, combining scientific progress, regulatory clarity, and environmental responsibility.

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